SRPR Antibody

• Background:

  The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  6734

• Swiss Prot:

  P08240

• Accession Number:

  P08240

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SRPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-480 amino acids from the C-terminal region of human SRPR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  70 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SRPR

• NCBI Official Name:

  Signal recognition particle receptor subunit alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Janin, N., et al. Hum. Genet. 88 (5) :583-585 (1992)

• Background Reference 02:

  Hortsch, M., et al. Biochem. Biophys. Res. Commun. 150 (1) :111-117 (1988)

• Background Reference 03:

  Hortsch, M., et al. Nucleic Acids Res. 16 (1) :361-362 (1988)

• Background Reference 04:

  Tajima, S., et al. J. Cell Biol. 103 (4) :1167-1178 (1986)

• Other Product Names:

  Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha, SRPR

• Tested Applications:

  WB

• Protein ID:

  20455516

• Physical Properties:

  Liquid