QTRT1 Antibody

• Background:

  TRNA-guanine transglycosylase (TGT; EC 2.4.2.29) synthesizes queuosine (Q), which is found in tRNAs that recognize NAU and NAC codons, encoding tyr, asn, asp, and his. Prokaryotic TGT is a single protein of 43 kD. In contrast, mammalian TGT appears to be a heterodimer consisting of a 60-kD subunit (USP14; MIM 607274) and a 43-kD catalytic subunit (QTRT1) (Deshpande and Katze, 2001 [PubMed 11255023]) .

• NCBI Gene ID:

  81890

• Swiss Prot:

  Q9BXR0

• Accession Number:

  Q9BXR0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This QTRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-371 amino acids from the C-terminal region of human QTRT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  QTRT1

• NCBI Official Name:

  Queuine tRNA-ribosyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chen, Y.C., et al. RNA 16 (5) :958-968 (2010)

• Background Reference 02:

  Deshpande, K.L., et al. Gene 265 (1-2), 205-212 (2001) :

• Other Product Names:

  Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase, QTRT1, TGT, TGUT

• Tested Applications:

  WB

• Protein ID:

  239938842

• Physical Properties:

  Liquid