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PNPT1 Antibody

CAT: 0223-59-288Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-288Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 [PubMed 12419256]) .
NCBI Gene ID
87178
Swiss Prot
Q8TCS8
Accession Number
Q8TCS8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PNPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PNPT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PNPT1
NCBI Official Name
Polyribonucleotide nucleotidyltransferase 1, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Wang, G., et al. Cell 142 (3) :456-467 (2010)
Background Reference 02
Das, S.K., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (26) :11948-11953 (2010)
Background Reference 03
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Background Reference 04
O'Doherty, C., et al. Pharmacogenomics 10 (7) :1177-1186 (2009)
Other Product Names
Polyribonucleotide nucleotidyltransferase 1, mitochondrial, 3'-5' RNA exonuclease OLD35, PNPase old-35, Polynucleotide phosphorylase 1, PNPase 1, Polynucleotide phosphorylase-like protein, PNPT1, PNPASE
Tested Applications
WB
Protein ID
115502437
Physical Properties
Liquid

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