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WDR4 Antibody

CAT: 0223-59-281Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-281Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
10785
Swiss Prot
P57081
Accession Number
P57081
Host
Rabbit
Reactivity
Human
Immunogen
This WDR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-173 amino acids from the Central region of human WDR4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WDR4
NCBI Official Name
TRNA (guanine-N (7) -) -methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
NCBI Organism
Homo sapiens
Background Reference 01
Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)
Background Reference 02
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 03
Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
Background Reference 04
Cartlidge, R.A., et al. EMBO J. 24 (9) :1696-1705 (2005)
Other Product Names
TRNA (guanine-N (7) -) -methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}, WD repeat-containing protein 4 {ECO:0000255|HAMAP-Rule:MF_03056}, WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}
Tested Applications
WB
Protein ID
20141943
Physical Properties
Liquid

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