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WDR45 Antibody

CAT: 0223-56-982Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-982Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
NCBI Gene ID
11152
Swiss Prot
Q9Y484
Accession Number
Q9Y484
Host
Rabbit
Reactivity
Human
Immunogen
This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human WDR45.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WDR45
NCBI Official Name
WD repeat domain phosphoinositide-interacting protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Proikas-Cezanne, T., et al. Oncogene 23 (58) :9314-9325 (2004)
Background Reference 02
Jeffries, T.R., et al. Mol. Biol. Cell 15 (6) :2652-2663 (2004)
Background Reference 03
Clark, A.G., et al. Science 302 (5652) :1960-1963 (2003)
Other Product Names
WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat-containing protein 45, WDR45, WDRX1, WDRXI4, WIPI4
Tested Applications
WB
Protein ID
74762056
Physical Properties
Liquid

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