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GLB1 Antibody

CAT: 0223-59-277Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-277Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2720
Swiss Prot
P16278
Accession Number
P16278
Host
Rabbit
Reactivity
Human
Immunogen
This GLB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human GLB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
76 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GLB1
NCBI Official Name
Beta-galactosidase
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)
Background Reference 03
Antonicelli, F., et al. Wound Repair Regen 17 (5) :631-638 (2009)
Background Reference 04
Hofer, D., et al. Hum. Mutat. 30 (8) :1214-1221 (2009)
Other Product Names
Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1, GLB1, ELNR1
Tested Applications
WB
Protein ID
215273939
Physical Properties
Liquid

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