GLB1 Antibody

• Background :

  This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  2720

• Swiss Prot :

  P16278

• Accession Number :

  P16278

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This GLB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human GLB1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  76 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  GLB1

• NCBI Official Name :

  Beta-galactosidase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02 :

  Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

• Background Reference 03 :

  Antonicelli, F., et al. Wound Repair Regen 17 (5) :631-638 (2009)

• Background Reference 04 :

  Hofer, D., et al. Hum. Mutat. 30 (8) :1214-1221 (2009)

• Other Product Names :

  Beta-galactosidase, Acid beta-galactosidase, Lactase, Elastin receptor 1, GLB1, ELNR1

• Tested Applications :

  WB

• Protein ID :

  215273939

• Physical Properties :

  Liquid