MTRF1 Antibody

• Background:

  The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq].

• NCBI Gene ID:

  9617

• Swiss Prot:

  O75570

• Accession Number:

  O75570

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MTRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of human MTRF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MTRF1

• NCBI Official Name:

  Peptide chain release factor 1, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Antonicka, H., et al. Am. J. Hum. Genet. 87 (1) :115-122 (2010)

• Background Reference 02:

  Nozaki, Y., et al. Genes Cells 13 (5) :429-438 (2008)

• Background Reference 03:

  Soleimanpour-Lichaei, H.R., et al. Mol. Cell 27 (5) :745-757 (2007)

• Background Reference 04:

  Hansen, L.L., et al. Cytogenet. Cell Genet. 88 (1-2), 91-92 (2000) :

• Other Product Names:

  Peptide chain release factor 1, mitochondrial, MRF-1, MtRF-1, MTRF1

• Tested Applications:

  WB

• Physical Properties:

  Liquid