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SMOC2 Antibody

CAT: 0223-59-218Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-218Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
NCBI Gene ID
64094
Swiss Prot
Q9H3U7
Accession Number
Q9H3U7
Host
Rabbit
Reactivity
Human
Immunogen
This SMOC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-431 amino acids from the C-terminal region of human SMOC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SMOC2
NCBI Official Name
SPARC-related modular calcium-binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Birlea, S.A., et al. J. Invest. Dermatol. 130 (3) :798-803 (2010)
Background Reference 03
Wilk, J.B., et al. Am. J. Respir. Crit. Care Med. 175 (6) :554-560 (2007)
Background Reference 04
Rocnik, E.F., et al. J. Biol. Chem. 281 (32) :22855-22864 (2006)
Other Product Names
SPARC-related modular calcium-binding protein 2, Secreted modular calcium-binding protein 2, SMOC-2, Smooth muscle-associated protein 2, SMAP-2, SMOC2, SMAP2
Tested Applications
WB
Protein ID
38258648
Physical Properties
Liquid

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