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QPCT Antibody

CAT: 0223-59-199Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-199Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.
NCBI Gene ID
25797
Swiss Prot
Q16769
Accession Number
Q16769
Host
Rabbit
Reactivity
Human
Immunogen
This QPCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the C-terminal region of human QPCT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
QPCT
NCBI Official Name
Glutaminyl-peptide cyclotransferase
NCBI Organism
Homo sapiens
Background Reference 01
Morawski, M., et al. Acta Neuropathol. 120 (2) :195-207 (2010)
Background Reference 02
Stephan, A., et al. FEBS J. 276 (22) :6522-6536 (2009)
Background Reference 03
Marroni, F., et al. Circ Cardiovasc Genet 2 (4) :322-328 (2009)
Background Reference 04
Calvaresi, M., et al. Proteins 73 (3) :527-538 (2008)
Other Product Names
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, sQC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC, QPCT
Tested Applications
WB
Protein ID
2498824
Physical Properties
Liquid

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