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PAFAH2 Antibody

CAT: 0223-59-174Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-174Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) . However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.
NCBI Gene ID
5051
Swiss Prot
Q99487
Accession Number
Q99487
Host
Rabbit
Reactivity
Human
Immunogen
This PAFAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the Central region of human PAFAH2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PAFAH2
NCBI Official Name
Platelet-activating factor acetylhydrolase 2, cytoplasmic
NCBI Organism
Homo sapiens
Background Reference 01
Schmidt, E.B., et al. Atherosclerosis 196 (1) :420-424 (2008)
Background Reference 02
Umemura, K., et al. Stroke 38 (3) :1063-1068 (2007)
Background Reference 03
Unno, N., et al. J. Surg. Res. 134 (1) :36-43 (2006)
Background Reference 04
Marques, M., et al. J. Invest. Dermatol. 119 (4) :913-919 (2002)
Other Product Names
Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2, PAFAH2
Tested Applications
WB
Protein ID
6647691
Physical Properties
Liquid

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