PRDM10 Antibody

• Background:

  The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

• NCBI Gene ID:

  56980

• Swiss Prot:

  Q9NQV6

• Accession Number:

  Q9NQV6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PRDM10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids from the Central region of human PRDM10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Zebrafish

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  130 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PRDM10

• NCBI Official Name:

  PR domain zinc finger protein 10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bhatti, P., et al. Radiat. Res. 173 (2) :214-224 (2010)

• Background Reference 02:

  Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)

• Background Reference 03:

  Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

• Background Reference 04:

  Siegel, D.A., et al. Int. J. Dev. Neurosci. 20 (3-5), 373-389 (2002) :

• Other Product Names:

  PR domain zinc finger protein 10, 211-, PR domain-containing protein 10, Tristanin, PRDM10, KIAA1231, PFM7, TRIS

• Tested Applications:

  WB

• Protein ID:

  442570289

• Physical Properties:

  Liquid