DAPP1 Antibody

• Background:

  DAPP1 may act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR) -signaling downstream of PI3K.

• NCBI Gene ID:

  27071

• Swiss Prot:

  Q9UN19

• Accession Number:

  Q9UN19

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DAPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-275 amino acids from the C-terminal region of human DAPP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  32 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DAPP1

• NCBI Official Name:

  Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Manna, D., et al. J. Biol. Chem. 282 (44) :32093-32105 (2007)

• Background Reference 02:

  Niiro, H., et al. J. Immunol. 173 (9) :5601-5609 (2004)

• Background Reference 03:

  Allam, A., et al. J. Biol. Chem. 279 (38) :39775-39782 (2004)

• Background Reference 04:

  Han, A., et al. Immunity 19 (4) :621-632 (2003)

• Other Product Names:

  Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, hDAPP1, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa, DAPP1, BAM32

• Tested Applications:

  WB

• Protein ID:

  51317293

• Physical Properties:

  Liquid