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ANP32C Antibody

CAT: 0223-59-136Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-136Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq].
NCBI Gene ID
23520
Swiss Prot
O43423
Accession Number
O43423
Host
Rabbit
Reactivity
Human
Immunogen
This ANP32C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-158 amino acids from the Central region of human ANP32C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
27 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ANP32C
NCBI Official Name
Acidic leucine-rich nuclear phosphoprotein 32 family member C
NCBI Organism
Homo sapiens
Background Reference 01
Matilla, A., et al. Cerebellum 4 (1) :7-18 (2005)
Background Reference 02
Kochevar, G.J., et al. Hum. Mutat. 23 (6) :546-551 (2004)
Background Reference 03
Fan, Z., et al. Nat. Immunol. 4 (2) :145-153 (2003)
Background Reference 04
Kadkol, S.S., et al. Breast Cancer Res. Treat. 68 (1) :65-73 (2001)
Other Product Names
Acidic leucine-rich nuclear phosphoprotein 32 family member C, Phosphoprotein 32-related protein 1, Tumorigenic protein pp32r1, ANP32C, PP32R1
Tested Applications
WB
Physical Properties
Liquid

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