Products for Research Use Only

LMBR1 Antibody

CAT: 0223-59-097Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-097Size:400 µL
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Background
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
NCBI Gene ID
64327
Swiss Prot
Q8WVP7
Accession Number
Q8WVP7
Host
Rabbit
Reactivity
Human
Immunogen
This LMBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human LMBR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LMBR1
NCBI Official Name
Limb region 1 protein homolog
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Farooq, M., et al. Eur. J. Hum. Genet. 18 (6) :733-736 (2010)
Background Reference 03
Rutsch, F., et al. Nat. Genet. 41 (2) :234-239 (2009)
Background Reference 04
He, F., et al. PLoS ONE (8), E2948 (2008) :
Other Product Names
Limb region 1 protein homolog, Differentiation-related gene 14 protein, LMBR1, C7orf2, DIF14
Tested Applications
WB
Protein ID
74730878
Physical Properties
Liquid