PGBD1 Antibody

• Background:

  The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.

• NCBI Gene ID:

  84547

• Swiss Prot:

  Q96JS3

• Accession Number:

  Q96JS3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PGBD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-375 amino acids from the Central region of human PGBD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  93 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PGBD1

• NCBI Official Name:

  PiggyBac transposable element-derived protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, T., et al. Biol. Psychiatry 68 (7) :671-673 (2010)

• Background Reference 02:

  Corneveaux, J.J., et al. Hum. Mol. Genet. 19 (16) :3295-3301 (2010)

• Background Reference 03:

  Schjeide, B.M., et al. Neurogenetics 10 (1) :19-25 (2009)

• Background Reference 04:

  Sarkar, A., et al. Mol. Genet. Genomics 270 (2) :173-180 (2003)

• Other Product Names:

  PiggyBac transposable element-derived protein 1, Cerebral protein 4, PGBD1

• Tested Applications:

  WB

• Protein ID:

  74751967

• Physical Properties:

  Liquid