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MCC Antibody

CAT: 0223-59-060Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-060Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4163
Swiss Prot
P23508
Accession Number
P23508
Host
Rabbit
Reactivity
Human
Immunogen
This MCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-501 amino acids from the Central region of human MCC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MCC
NCBI Official Name
Colorectal mutant cancer protein
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)
Background Reference 03
Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)
Background Reference 04
Arnaud, C., et al. FEBS Lett. 583 (14) :2326-2332 (2009)
Other Product Names
Colorectal mutant cancer protein, Protein MCC, MCC
Tested Applications
WB
Protein ID
317373352
Physical Properties
Liquid

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