PDGFC Antibody

• Background:

  Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.

• NCBI Gene ID:

  56034

• Swiss Prot:

  Q9NRA1

• Accession Number:

  Q9NRA1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PDGFC

• NCBI Official Name:

  Platelet-derived growth factor C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24 (4) :787-792 (2004) . Clark, H.F., et al., Genome Res. 13 (10) :2265-2270 (2003) . Eitner, F., et al., J. Am. Soc. Nephrol. 14 (5) :1145-1153 (2003) . Reigstad, L.J., et al., J. Biol. Chem. 278 (19) :17114-17120 (2003) . Zwerner, J.P., et al., Oncogene 21 (24) :3847-3854 (2002) .

• Other Product Names:

  Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, PDGFC, SCDGF

• Tested Applications:

  WB, IHC-P

• Protein ID:

  205830662

• Physical Properties:

  Liquid