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RHD Antibody

CAT: 0223-59-029Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-029Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
6007
Swiss Prot
Q02161
Accession Number
Q02161
Host
Rabbit
Reactivity
Human
Immunogen
This RHD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-201 amino acids from the Central region of human RHD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
RHD
NCBI Official Name
Blood group Rh (D) polypeptide
NCBI Organism
Homo sapiens
Background Reference 01
Flegr, J., et al. Folia Parasitol. 57 (2) :143-150 (2010)
Background Reference 02
Liu, H.C., et al. Biochim. Biophys. Acta 1800 (6) :565-573 (2010)
Background Reference 03
Schmid, P., et al. Transfusion 50 (1) :267-269 (2010)
Background Reference 04
Wang, X.D., et al. Eur. J. Clin. Invest. 39 (7) :607-617 (2009)
Other Product Names
Blood group Rh (D) polypeptide, RHXIII, Rh polypeptide 2, RhPII, Rhesus D antigen, CD240D, RHD
Tested Applications
WB
Protein ID
296452980
Physical Properties
Liquid

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