H1FOO Antibody

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.

• NCBI Gene ID:

  132243

• Swiss Prot:

  Q8IZA3

• Accession Number:

  Q8IZA3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This H1FOO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the Central region of human H1FOO.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  H1FOO

• NCBI Official Name:

  Histone H1oo

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mizusawa, Y., et al. Fertil. Steril. 93 (4) :1134-1141 (2010)

• Background Reference 02:

  Tanaka, M., et al. Biol. Reprod. 72 (1) :135-142 (2005)

• Background Reference 03:

  Teranishi, T., et al. Dev. Biol. 266 (1) :76-86 (2004)

• Background Reference 04:

  Gao, S., et al. Dev. Biol. 266 (1) :62-75 (2004)

• Other Product Names:

  Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1, H1FOO, H1OO, OSH1

• Tested Applications:

  WB

• Protein ID:

  74762503

• Physical Properties:

  Liquid