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DNAJA2 Antibody

CAT: 0223-58-956Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-956Size:400 µL
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Background
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F) -rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
NCBI Gene ID
10294
Swiss Prot
O60884
Accession Number
O60884
Host
Rabbit
Reactivity
Human
Immunogen
This DNAJA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human DNAJA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DNAJA2
NCBI Official Name
DnaJ homolog subfamily A member 2
NCBI Organism
Homo sapiens
Background Reference 01
Walker, V.E., et al. J. Biol. Chem. 285 (5) :3319-3329 (2010)
Background Reference 02
Rosales-Hernandez, A., et al. Cell Stress Chaperones 14 (1) :71-82 (2009)
Background Reference 03
Tzankov, S., et al. J. Biol. Chem. 283 (40) :27100-27109 (2008)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
DnaJ homolog subfamily A member 2, Cell cycle progression restoration gene 3 protein, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, DNAJA2, CPR3, HIRIP4
Tested Applications
WB
Physical Properties
Liquid

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