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DNAJA4 Antibody

CAT: 0223-8141-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-8141-01Size:0.02 mg
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Background
The DNAJA4 protein is the mammalian homolog of the chaperone HSP40 (1) and acts as a co-chaperone with the heat shock protein HSP70 (2) . DNAJA4 is highly expressed in heart and testis, accounting for approximately 1% of total protein in mouse heart (2) . DNAJA4 is also regulated by the sterol regulatory element binding transcription factor 2 (SREBF2) and plays a role in the synthesis of cholesterol (3) .
NCBI Gene ID
55466
Swiss Prot
Q8WW22
Accession Number
NP_061072
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
DNAJA4 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1320 - Human Colon Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (87%)
Buffer
DNAJA4 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DNAJA4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
DNAJA4 antibody is human, mouse, and rat reactive. At least three isoforms of DNAJA4 are known to exist; this antibody will detect all three isoforms.
Symbol
DNAJA4
NCBI Official Name
DnaJ homolog subfamily A member 4
NCBI Organism
Homo sapiens
Background Reference 01
Ohtsuka K and Hata M. Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones 2000; 5:98-112.
Background Reference 02
Abdul KM, Terada K, Gotoh T, et al. Characterization and functional analysis of a heart-enriched DnaJ / Hsp40 homolog dj4/DjA4. Cell Stress Chaperones 2002; 7:156-66.
Background Reference 03
Robichon C, Varret M, Le Liepvre X, et al. DnajA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway. Biochim. Biophys. Acta 2006; 1761:1107-13.
Other Product Names
DnaJ homolog subfamily A member 4, MST104, MSTP104, PRO1472
Tested Applications
ELISA, WB
Protein ID
194328758
Physical Properties
Liquid

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