SUOX Antibody

• Background:

  Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.

• NCBI Gene ID:

  6821

• Swiss Prot:

  P51687

• Accession Number:

  P51687

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SUOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-187 amino acids from the Central region of human SUOX.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  60 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SUOX

• NCBI Official Name:

  Sulfite oxidase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rajapakshe, A., et al. Biochemistry 49 (25) :5154-5159 (2010)

• Background Reference 02:

  Johnson-Winters, K., et al. Biochemistry 49 (6) :1290-1296 (2010)

• Background Reference 03:

  Neumann, M., et al. FEBS J. 275 (22) :5678-5689 (2008)

• Background Reference 04:

  Astashkin, A.V., et al. J. Am. Chem. Soc. 130 (26) :8471-8480 (2008)

• Other Product Names:

  Sulfite oxidase, mitochondrial, SUOX

• Tested Applications:

  WB

• Protein ID:

  152031695

• Physical Properties:

  Liquid