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HAND2 Antibody

CAT: 0223-58-872Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-872Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
NCBI Gene ID
9464
Swiss Prot
P61296
Accession Number
P61296
Host
Rabbit
Reactivity
Human
Immunogen
This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human HAND2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
HAND2
NCBI Official Name
Heart- and neural crest derivatives-expressed protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Shen, L., et al. Chin. Med. J. 123 (13) :1623-1627 (2010)
Background Reference 02
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 03
Voth, H., et al. BMC Mol. Biol. 10, 28 (2009) :
Background Reference 04
Morikawa, Y., et al. Circ. Res. 103 (12) :1422-1429 (2008)
Other Product Names
Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND, HAND2, BHLHA26, DHAND
Tested Applications
WB, IF
Protein ID
47117699
Physical Properties
Liquid

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