PPP1CC Antibody

CAT: 0223-58-851Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-851Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca (2+) /calmodulin dependent protein kinase II.
NCBI Gene ID
5501
Swiss Prot
P36873
Accession Number
P36873
Host
Rabbit
Reactivity
Human
Immunogen
This PPP1CC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human PPP1CC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
37 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP1CC
NCBI Official Name
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
NCBI Organism
Homo sapiens
Background Reference 01
Lee, J.H., et al. J. Biol. Chem. 285 (32) :24466-24476 (2010)
Background Reference 02
Kuzmin, A., et al. Biol. Reprod. 81 (2) :319-326 (2009)
Background Reference 03
Fujiki, R., et al. Nature 459 (7245) :455-459 (2009)
Background Reference 04
Rogne, M., et al. Hum. Mol. Genet. 18 (5) :978-987 (2009)
Other Product Names
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, PP-1G, Protein phosphatase 1C catalytic subunit, PPP1CC
Tested Applications
WB
Protein ID
548573
Physical Properties
Liquid

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