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SRM Antibody

CAT: 0223-58-831Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-831Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
NCBI Gene ID
6723
Swiss Prot
P19623
Accession Number
P19623
Host
Rabbit
Reactivity
Human
Immunogen
This SRM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SRM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SRM
NCBI Official Name
Spermidine synthase
NCBI Organism
Homo sapiens
Background Reference 01
Wu, H., et al. Biochemistry 46 (28) :8331-8339 (2007)
Background Reference 02
Nishikawa, Y., et al. Biochem. J. 321 (PT 2), 537-543 (1997) :
Background Reference 03
Lakanen, J.R., et al. J. Med. Chem. 38 (14) :2714-2727 (1995)
Background Reference 04
Kauppinen, L. FEBS Lett. 365 (1) :61-65 (1995)
Other Product Names
Spermidine synthase, SPDSY, Putrescine aminopropyltransferase, SRM, SPS1, SRML1
Tested Applications
WB
Protein ID
134811
Physical Properties
Liquid

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