FKBP6 Antibody

• Background:

  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis.

• NCBI Gene ID:

  8468

• Swiss Prot:

  O75344

• Accession Number:

  O75344

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FKBP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-284 amino acids from the C-terminal region of human FKBP6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  FKBP6

• NCBI Official Name:

  Inactive peptidyl-prolyl cis-trans isomerase FKBP6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Aston, K.I., et al. Hum. Reprod. 25 (6) :1383-1397 (2010)

• Background Reference 02:

  Jarczowski, F., et al. J. Biol. Chem. 284 (2) :766-773 (2009)

• Background Reference 03:

  Jarczowski, F., et al. Biochemistry 47 (26) :6946-6952 (2008)

• Background Reference 04:

  Zhang, W., et al. Reproduction 133 (2) :511-516 (2007)

• Other Product Names:

  Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, 36 kDa FKBP, FKBP-36, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36, FKBP6, FKBP36

• Tested Applications:

  WB

• Physical Properties:

  Liquid