GPLD1 Antibody

• Background:

  Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.

• NCBI Gene ID:

  2822

• Swiss Prot:

  P80108

• Accession Number:

  P80108

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GPLD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-306 amino acids from the Central region of human GPLD1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  92 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GPLD1

• NCBI Official Name:

  Phosphatidylinositol-glycan-specific phospholipase D

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)

• Background Reference 02:

  Tang, J.H., et al. Clin. Biochem. 42 (4-5), 400-407 (2009) :

• Background Reference 03:

  Yuan, X., et al. Am. J. Hum. Genet. 83 (4) :520-528 (2008)

• Background Reference 04:

  Wright, M.H., et al. Biochem. Biophys. Res. Commun. 369 (2) :478-484 (2008)

• Other Product Names:

  Phosphatidylinositol-glycan-specific phospholipase D, PI-G PLD, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, GPLD1, PIGPLD1

• Tested Applications:

  WB

• Protein ID:

  126302583

• Physical Properties:

  Liquid