GPLD1 Antibody

CAT: 0223-58-803Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-803Size:400 µL
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Background
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane.
NCBI Gene ID
2822
Swiss Prot
P80108
Accession Number
P80108
Host
Rabbit
Reactivity
Human
Immunogen
This GPLD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-306 amino acids from the Central region of human GPLD1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GPLD1
NCBI Official Name
Phosphatidylinositol-glycan-specific phospholipase D
NCBI Organism
Homo sapiens
Background Reference 01
Speliotes, E.K., et al. Hepatology 52 (3) :904-912 (2010)
Background Reference 02
Tang, J.H., et al. Clin. Biochem. 42 (4-5), 400-407 (2009) :
Background Reference 03
Yuan, X., et al. Am. J. Hum. Genet. 83 (4) :520-528 (2008)
Background Reference 04
Wright, M.H., et al. Biochem. Biophys. Res. Commun. 369 (2) :478-484 (2008)
Other Product Names
Phosphatidylinositol-glycan-specific phospholipase D, PI-G PLD, Glycoprotein phospholipase D, Glycosyl-phosphatidylinositol-specific phospholipase D, GPI-PLD, GPI-specific phospholipase D, GPLD1, PIGPLD1
Tested Applications
WB
Protein ID
126302583
Physical Properties
Liquid

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