TSFM Antibody

• Background:

  This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.

• NCBI Gene ID:

  10102

• Swiss Prot:

  P43897

• Accession Number:

  P43897

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TSFM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the C-terminal region of human TSFM.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TSFM

• NCBI Official Name:

  Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, W., et al. Nucleic Acids Res. (2010) In press :

• Background Reference 02:

  Smeitink, J.A., et al. Am. J. Hum. Genet. 79 (5) :869-877 (2006)

• Background Reference 03:

  Antonicka, H., et al. Hum. Mol. Genet. 15 (11) :1835-1846 (2006)

• Background Reference 04:

  Vernon, J.L., et al. Cytogenet. Cell Genet. 89 (3-4), 145-146 (2000) :

• Other Product Names:

  Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}, EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}, EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}, TSFM {ECO:0000255|HAMAP-Rule:MF_03135}

• Tested Applications:

  WB

• Protein ID:

  12644268

• Physical Properties:

  Liquid