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SH3BGR Antibody

CAT: 0223-58-788Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-788Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. SH3 domain binding glutamic acid-rich protein (SH3BGR), also designated 21-glutamic acid-rich protein (21-GARP), is a 239-amino acid protein differentially expressed in heart and skeletal muscle. Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure. SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.
NCBI Gene ID
6450
Swiss Prot
P55822
Accession Number
P55822
Host
Rabbit
Reactivity
Human
Immunogen
This SH3BGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human SH3BGR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SH3BGR
NCBI Official Name
SH3 domain-binding glutamic acid-rich protein
NCBI Organism
Homo sapiens
Background Reference 01
Naukkarinen, J., et al. PLoS Genet. (6), E1000976 (2010) :
Background Reference 02
Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
Background Reference 03
Sandri, C., et al. Hum. Genet. 114 (5) :517-519 (2004)
Background Reference 04
Jiang, L.Q., et al. Hypertens. Res. 25 (4) :647-652 (2002)
Other Product Names
SH3 domain-binding glutamic acid-rich protein, SH3BGR protein, 21-glutamic acid-rich protein, 21-GARP, SH3BGR
Tested Applications
WB
Protein ID
215274184
Physical Properties
Liquid

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