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WTAP Antibody

CAT: 0223-58-781Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-781Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.
NCBI Gene ID
9589
Swiss Prot
Q15007
Accession Number
Q15007
Host
Rabbit
Reactivity
Human
Immunogen
This WTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human WTAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WTAP
NCBI Official Name
Pre-mRNA-splicing regulator WTAP
NCBI Organism
Homo sapiens
Background Reference 01
Su, J., et al. Diabetes Res. Clin. Pract. 87 (2) :167-175 (2010)
Background Reference 02
Small, T.W., et al. J. Biol. Chem. 284 (37) :24684-24695 (2009)
Background Reference 03
Benyamin, B., et al. Am. J. Hum. Genet. 84 (1) :60-65 (2009)
Background Reference 04
Zhong, S., et al. Plant Cell 20 (5) :1278-1288 (2008)
Other Product Names
Pre-mRNA-splicing regulator WTAP, Female-lethal (2) D homolog, hFL (2) D, WT1-associated protein, Wilms tumor 1-associating protein, WTAP, KIAA0105
Tested Applications
WB
Protein ID
47117889
Physical Properties
Liquid

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