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MGLL Antibody

CAT: 0223-58-776Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-776Size:400 µL
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Background
Monoglyceride lipase (MGLL; EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]) .[supplied by OMIM].
NCBI Gene ID
11343
Swiss Prot
Q99685
Accession Number
Q99685
Host
Rabbit
Reactivity
Human
Immunogen
This MGLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human MGLL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MGLL
NCBI Official Name
Monoglyceride lipase
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Karageorgos, I., et al. Mol Biosyst 6 (8) :1381-1388 (2010)
Background Reference 03
Bertrand, T., et al. J. Mol. Biol. 396 (3) :663-673 (2010)
Background Reference 04
Labar, G., et al. Chembiochem 11 (2) :218-227 (2010)
Other Product Names
Monoglyceride lipase, MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL
Tested Applications
WB
Protein ID
47117287
Physical Properties
Liquid

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