DCDC2 Antibody

• Background:

  This gene encodes a protein with two doublecortin peptide domains. This domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia.

• NCBI Gene ID:

  51473

• Swiss Prot:

  Q9UHG0

• Accession Number:

  Q9UHG0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DCDC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-334 amino acids from the Central region of human DCDC2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DCDC2

• NCBI Official Name:

  Doublecortin domain-containing protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Couto, J.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (2), 447-462 (2010) :

• Background Reference 02:

  Meda, S.A., et al. Neuroimage (2009) In press :

• Background Reference 03:

  Couto, J.M., et al. Biol. Psychiatry 66 (4) :368-375 (2009)

• Background Reference 04:

  Wilcke, A., et al. Ann Dyslexia 59 (1) :1-11 (2009)

• Other Product Names:

  Doublecortin domain-containing protein 2, Protein RU2S, DCDC2, KIAA1154, RU2

• Tested Applications:

  WB

• Protein ID:

  147744557

• Physical Properties:

  Liquid