BSDC1 Antibody

CAT: 0223-58-755Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-755Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BSDC1 is a 430 amino acid protein encoded by a gene mapping to chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
NCBI Gene ID
55108
Swiss Prot
Q9NW68
Accession Number
Q9NW68
Host
Rabbit
Reactivity
Human
Immunogen
This BSDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-425 amino acids from the C-terminal region of human BSDC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BSDC1
NCBI Official Name
BSD domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Background Reference 02
Fu, G.K., et al. Genomics 84 (1) :205-210 (2004)
Background Reference 03
Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)
Other Product Names
BSD domain-containing protein 1, BSDC1
Tested Applications
WB
Protein ID
74753009
Physical Properties
Liquid

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