GGPS1 Antibody

• Background:

  This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq].

• NCBI Gene ID:

  9453

• Swiss Prot:

  O95749

• Accession Number:

  O95749

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GGPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the Central region of human GGPS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GGPS1

• NCBI Official Name:

  Geranylgeranyl pyrophosphate synthase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Choi, H.J., et al. Yonsei Med. J. 51 (2) :231-238 (2010)

• Background Reference 02:

  Raz, T., et al. Blood 110 (6) :2102-2109 (2007)

• Background Reference 03:

  Miyagi, Y., et al. J. Biochem. 142 (3) :377-381 (2007)

• Background Reference 04:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Other Product Names:

  Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E,6E) -farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1

• Tested Applications:

  WB

• Physical Properties:

  Liquid