ARL1 Antibody

CAT: 0223-58-726Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-726Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs) . ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
NCBI Gene ID
400
Swiss Prot
P40616
Accession Number
P40616
Host
Rabbit
Reactivity
Human
Immunogen
This ARL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human ARL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARL1
NCBI Official Name
ADP-ribosylation factor-like protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Houghton, F.J., et al. Cell 138 (4) :787-794 (2009)
Background Reference 02
Nishimoto-Morita, K., et al. J. Biol. Chem. 284 (16) :10583-10592 (2009)
Background Reference 03
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 04
Zahn, C., et al. Mol. Membr. Biol. 23 (6) :475-485 (2006)
Other Product Names
ADP-ribosylation factor-like protein 1, ARL1
Tested Applications
WB
Protein ID
728888
Physical Properties
Liquid

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