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EIF3K Antibody

CAT: 0223-58-722Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-722Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]) .
NCBI Gene ID
27335
Swiss Prot
Q9UBQ5
Accession Number
Q9UBQ5
Host
Rabbit
Reactivity
Human
Immunogen
This EIF3K antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the C-terminal region of human EIF3K.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EIF3K
NCBI Official Name
Eukaryotic translation initiation factor 3 subunit K {ECO:0000255|HAMAP-Rule:MF_03010}
NCBI Organism
Homo sapiens
Background Reference 01
Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (47) :18139-18144 (2008)
Background Reference 02
Lin, Y.M., et al. J. Cell. Sci. 121 (PT 14), 2382-2393 (2008) :
Background Reference 03
Masutani, M., et al. EMBO J. 26 (14) :3373-3383 (2007)
Background Reference 04
Damoc, E., et al. Mol. Cell Proteomics 6 (7) :1135-1146 (2007)
Other Product Names
Eukaryotic translation initiation factor 3 subunit K {ECO:0000255|HAMAP-Rule:MF_03010}, eIF3k {ECO:0000255|HAMAP-Rule:MF_03010}, Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000255|HAMAP-Rule:MF_03010}, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25 {ECO:0000255|HAMAP-Rule:MF_03010}, eIF-3 p28, EIF3K {ECO:0000255|HAMAP-Rule:MF_03010}
Tested Applications
WB
Protein ID
23396628
Physical Properties
Liquid

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