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DNAI1 Antibody

CAT: 0223-58-705Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-705Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
NCBI Gene ID
27019
Swiss Prot
Q9UI46
Accession Number
Q9UI46
Host
Rabbit
Reactivity
Human
Immunogen
This DNAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human DNAI1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DNAI1
NCBI Official Name
Dynein intermediate chain 1, axonemal
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Leigh, M.W., et al. Curr. Opin. Pediatr. 21 (3) :320-325 (2009)
Background Reference 03
Zuccarello, D., et al. Hum. Reprod. 23 (8) :1957-1962 (2008)
Background Reference 04
Failly, M., et al. Respiration 76 (2) :198-204 (2008)
Other Product Names
Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1, DNAI1
Tested Applications
WB
Protein ID
12643888
Physical Properties
Liquid

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