BAT3 Antibody

• Background:

  This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  7917

• Swiss Prot:

  P46379

• Accession Number:

  P46379

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1072-1099 amino acids from the C-terminal region of human BAT3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  119 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BAG6

• NCBI Official Name:

  Large proline-rich protein BAG6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02:

  Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16 (10) :770-777 (2010)

• Background Reference 03:

  Minami, R., et al. J. Cell Biol. 190 (4) :637-650 (2010)

• Background Reference 04:

  Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

• Other Product Names:

  Large proline-rich protein BAG6, BAG family molecular chaperone regulator 6, BCL2-associated athanogene 6, BAG-6, BAG6, HLA-B-associated transcript 3, Protein G3, Protein Scythe, BAG6, BAT3, G3

• Tested Applications:

  WB

• Protein ID:

  76800648

• Physical Properties:

  Liquid