BAT1 Antibody

CAT: 0223-28-485Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-485Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BAT1 is a member of the DEAD protein family of ATP-dependent RNA helicases. Members of this family are involved in a number of cellular functions including initiation of translation, RNA splicing, and ribosome assembly. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This protein is a negative regulator of inflammation. It is also thought to be a translation initiation factor. This gene is a strong candidate gene for rheumatoid arthritis. There are multiple alternatively spliced transcript variants known for this gene but only two have been fully described. Both of these variants encode the same isoform. This gene has been found to have multiple polyadenylation sites.
NCBI Gene ID
7919
Swiss Prot
Q13838
Accession Number
NP_542165
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Homeostasis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BAT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
47 kDa, 49 kDa, 49 kDa
Applications Notes
BAT1 antibody can be used for detection of BAT1 by ELISA at 1:12500. BAT1 antibody can be used for detection of BAT1 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DDX39B
NCBI Official Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
NCBI Organism
Homo sapiens
Background Reference 01
Allcock, R.J., et al., (2001) Genes Cells 6 (5), 487-494.
Other Product Names
BAT1, BAT1, UAP56, D6S81E
Tested Applications
ELISA, WB
Protein ID
18375623
Physical Properties
Liquid

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