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CLK2 Antibody

CAT: 0223-58-679Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-679Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.
NCBI Gene ID
1196
Swiss Prot
P49760
Accession Number
P49760
Host
Rabbit
Reactivity
Human
Immunogen
This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CLK2
NCBI Official Name
Dual specificity protein kinase CLK2
NCBI Organism
Homo sapiens
Background Reference 01
Nam, S.Y., et al. J. Biol. Chem. 285 (41) :31157-31163 (2010)
Background Reference 02
Eisenreich, A., et al. Circ. Res. 104 (5) :589-599 (2009)
Background Reference 03
Rendtlew Danielsen, J.M., et al. J. Biol. Chem. 284 (7) :4140-4147 (2009)
Background Reference 04
Castle, J.C., et al. Nat. Genet. 40 (12) :1416-1425 (2008)
Other Product Names
Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
Tested Applications
WB
Protein ID
1705919
Physical Properties
Liquid

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