CCNG2 Antibody

• Background:

  The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.

• NCBI Gene ID:

  901

• Swiss Prot:

  Q16589

• Accession Number:

  Q16589

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CCNG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the Central region of human CCNG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CCNG2

• NCBI Official Name:

  Cyclin-G2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 02:

  Choi, M.G., et al. J. Surg. Res. 157 (2) :168-174 (2009)

• Background Reference 03:

  Cunningham, J.M., et al. Br. J. Cancer 101 (8) :1461-1468 (2009)

• Background Reference 04:

  Xu, G., et al. Mol. Biol. Cell 19 (11) :4968-4979 (2008)

• Other Product Names:

  Cyclin-G2, CCNG2

• Tested Applications:

  WB

• Protein ID:

  9087132

• Physical Properties:

  Liquid