CCNG1 Antibody

• Background:

  The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].

• NCBI Gene ID:

  900

• Swiss Prot:

  P51959

• Accession Number:

  P51959

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This CCNG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-272 amino acids from the C-terminal region of human CCNG1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CCNG1

• NCBI Official Name:

  Cyclin-G1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cunningham, J.M., et al. Br. J. Cancer 101 (8) :1461-1468 (2009) Fornari, F., et al. Cancer Res. 69 (14) :5761-5767 (2009) Li, H., et al. Mol. Cell. Biol. 29 (3) :919-928 (2009) Piscopo, D.M., et al. Cancer Res. 68 (14) :5581-5590 (2008) Seo, H.R., et al. J. Biol. Chem. 283 (23) :15601-15610 (2008)

• Other Product Names:

  Cyclin-G1, Cyclin-G, CCNG1, CCNG, CYCG1

• Tested Applications:

  WB, Flow

• Protein ID:

  2506334

• Physical Properties:

  Liquid