CCNA2 Antibody

• Background :

  CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

• NCBI Gene ID :

  890

• Swiss Prot :

  P20248

• Accession Number :

  P20248

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human CCNA2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  49 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CCNA2

• NCBI Official Name :

  Cyclin-A2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Henglein B., Proc. Natl. Acad. Sci. U.S.A. 91:5490-5494 (1994)

• Background Reference 02 :

  Wang J., Nature 343:555-557 (1990)

• Background Reference 03 :

  Tsang, W.Y., J. Cell Biol. 178 (4), 621-633 (2007)

• Other Product Names :

  Cyclin-A2, Cyclin-A, CCNA2, CCN1, CCNA

• Tested Applications :

  WB, IHC-P

• Protein ID :

  311033358

• Physical Properties :

  Liquid