CPNE3 Antibody

• Background:

  Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the carboxy-terminus. The A domain mediates interactions between integrins and extracellular ligands.

• NCBI Gene ID:

  8895

• Swiss Prot:

  O75131

• Accession Number:

  O75131

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CPNE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 507-533 amino acids from the C-terminal region of human CPNE3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  60 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CPNE3

• NCBI Official Name:

  Copine-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Heinrich, C., et al. Oncogene 29 (11) :1598-1610 (2010)

• Background Reference 02:

  Thomas, G., et al. Nat. Genet. 40 (3) :310-315 (2008)

• Background Reference 03:

  Cowland, J.B., et al. J. Leukoc. Biol. 74 (3) :379-388 (2003)

• Background Reference 04:

  Caudell, E.G., et al. Biochemistry 39 (42) :13034-13043 (2000)

• Other Product Names:

  Copine-3, Copine III, CPNE3, CPN3, KIAA0636

• Tested Applications:

  WB

• Physical Properties:

  Liquid