H2BFWT Antibody

CAT: 0223-58-632Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-632Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.
NCBI Gene ID
158983
Swiss Prot
Q7Z2G1
Accession Number
Q7Z2G1
Host
Rabbit
Reactivity
Human
Immunogen
This H2BFWT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-88 amino acids from the Central region of human H2BFWT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
H2BFWT
NCBI Official Name
Histone H2B type W-T
NCBI Organism
Homo sapiens
Background Reference 01
Lee, J., et al. J. Cell. Mol. Med. 13 (8B), 1942-1951 (2009) :
Background Reference 02
Boulard, M., et al. Mol. Cell. Biol. 26 (4) :1518-1526 (2006)
Background Reference 03
Churikov, D., et al. Genomics 84 (4) :745-756 (2004)
Background Reference 04
Churikov, D., et al. Cytogenet. Genome Res. 105 (2-4), 203-214 (2004) :
Other Product Names
Histone H2B type W-T, H2B histone family member W testis-specific, H2BFWT
Tested Applications
WB
Protein ID
223590216
Physical Properties
Liquid

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