RBAK Antibody

• Background:

  This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.

• NCBI Gene ID:

  10053395257786

• Swiss Prot:

  Q9NYW8

• Accession Number:

  Q9NYW8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RBAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human RBAK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  83 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RBAK

• NCBI Official Name:

  RB-associated KRAB zinc finger protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)

• Background Reference 02:

  Ma, Y., et al. BMC Genomics 10, 109 (2009) :

• Background Reference 03:

  Jeske, Y.W., et al. Clin. Exp. Pharmacol. Physiol. 35 (4) :380-385 (2008)

• Background Reference 04:

  So, A., et al. Clin. Endocrinol. (Oxf) 65 (6) :829-831 (2006)

• Other Product Names:

  RB-associated KRAB zinc finger protein, RB-associated KRAB repressor, hRBaK, Zinc finger protein 769, RBAK, ZNF769

• Tested Applications:

  WB

• Protein ID:

  74761820

• Physical Properties:

  Liquid