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PLA2G12A Antibody

CAT: 0223-58-615Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-615Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]) .
NCBI Gene ID
81579
Swiss Prot
Q9BZM1
Accession Number
Q9BZM1
Host
Rabbit
Reactivity
Human
Immunogen
This PLA2G12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human PLA2G12A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PLA2G12A
NCBI Official Name
Group XIIA secretory phospholipase A2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Kalsi, G., et al. Hum. Mol. Genet. 19 (12) :2497-2506 (2010)
Background Reference 03
Chen, W., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (16) :7401-7406 (2010)
Background Reference 04
Hosgood, H.D. III, et al. Occup Environ Med 66 (12) :848-853 (2009)
Other Product Names
Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A, PLA2G12A, PLA2G12
Tested Applications
WB
Protein ID
20143881
Physical Properties
Liquid

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