PLA2G1B Antibody

• Background:

  This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs) . The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.

• NCBI Gene ID:

  5319

• Swiss Prot:

  P04054

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 23-148 of human PLA2G1B (NP_000919.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 16kDa

• Fragment:

  IgG

• Symbol:

  PLA2G1B

• Positive Control 2:

  Mouse pancreas

• Positive Control 3:

  Mouse small intestine

• NCBI Official Name:

  Phospholipase A2, group IB (pancreas)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PLA2G1B, phospholipase A2, group IB (pancreas), MGC119834, MGC119835, PLA2, PLA2A, PPLA2, group IB

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid