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EPB49 Antibody

CAT: 0223-58-591Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-591Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation (Rana et al., 1993 [PubMed 8341682]) .
NCBI Gene ID
2039
Swiss Prot
Q08495
Accession Number
Q08495
Host
Rabbit
Reactivity
Human
Immunogen
This EPB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human EPB49.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DMTN
NCBI Official Name
Dematin
NCBI Organism
Homo sapiens
Background Reference 01
Vugmeyster, L., et al. J. Biomol. NMR 47 (2) :155-162 (2010)
Background Reference 02
Chen, L., et al. Protein Sci. 18 (3) :629-636 (2009)
Background Reference 03
Vugmeyster, L., et al. J. Biomol. NMR 43 (1) :39-50 (2009)
Background Reference 04
Vermeulen, W., et al. J. Mol. Biol. 359 (5) :1277-1292 (2006)
Other Product Names
Dematin, Dematin actin-binding protein, Erythrocyte membrane protein band 49, DMTN, DMT, EPB49
Tested Applications
WB
Protein ID
22654240
Physical Properties
Liquid

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