PPP1R9B Antibody

• Background:

  Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1; see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997 [PubMed 9275233]) .

• NCBI Gene ID:

  84687

• Swiss Prot:

  Q96SB3

• Accession Number:

  Q96SB3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPP1R9B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human PPP1R9B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  89 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPP1R9B

• NCBI Official Name:

  Neurabin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

• Background Reference 02:

  Rajagopal, S., et al. J. Biol. Chem. 285 (23) :18060-18071 (2010)

• Background Reference 03:

  Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259 (3) :151-163 (2009)

• Background Reference 04:

  Sagara, M., et al. Oncogene 28 (10) :1357-1365 (2009)

• Other Product Names:

  Neurabin-2, Neurabin-II, Protein phosphatase 1 regulatory subunit 9B, Spinophilin, PPP1R9B, PPP1R6

• Tested Applications:

  WB

• Protein ID:

  90101416

• Physical Properties:

  Liquid